What is Diosmin?
- Natures Supplement
- Dec 24, 2024
- 2 min read
Diosmin is a flavonoid compound primarily found in citrus fruits known for its antioxidant and anti-inflammatory properties[1][4]. It was first isolated from the figwort plant in 1925 and has been used since 1969 as a natural therapy for various circulatory issues[1].
Uses and Benefits of Diosmin
Diosmin is commonly used to treat:
1. Hemorrhoids
2. Varicose veins
3. Chronic venous insufficiency
4. Leg ulcers
5. Poor circulation in the legs (venous stasis)[1][2]
It may also be beneficial for:
- Reducing swelling in arms (lymphedema) following breast cancer surgery
- Protecting against liver toxicity
Mechanism of Action
Diosmin works by:
- Reducing inflammation and swelling
- Restoring normal vein function
- Improving lymphatic drainage and microcirculation
Dosage and Administration
The typical dosage of diosmin is 1,000 mg orally daily, divided into two doses for short durations (3 months or less)[3]. It is often combined with hesperidin in a micronized form, known as micronized purified flavonoid fraction (MPFF)[3].
Safety and Side Effects
Diosmin generally has a favorable safety profile[4]. However, as with any supplement, it's essential to consult a healthcare professional before use, especially if you have any underlying health conditions or are taking other medications.
Yes, there are known side effects associated with taking diosmin, although they are generally considered mild and infrequent. The most common side effects include:
1. Stomach pain and upset
2. Diarrhea
3. Headache
4. Dizziness
5. Skin rash or hives
6. Muscle pain
In rare and severe cases, diosmin may cause:
7. Irregular heartbeat
8. Blood problems
It's important to note that diosmin is generally considered safe for most people when used short-term (up to three months)[7]. However, if you experience any side effects, it's recommended to discontinue use and consult with a healthcare provider[8]. If you experience severe pain, severe diarrhea (10 or more loose stools in 24 hours), or an irregular heartbeat, seek immediate medical attention[8].
As with any supplement, it's advisable to consult a healthcare professional before starting diosmin, especially if you have any underlying health conditions or are taking other medications[9].
Research and Potential
Recent studies have explored diosmin's potential in various areas:
- Cancer: Diosmin has shown anti-cancer properties in several cell types, including breast, prostate, skin, and colon cancer cells[4].
- Diabetes: It may have therapeutic effects on diabetes and related complications like neuropathy and dyslipidemia[4].
- Antimicrobial activity: Some evidence suggests weak antimicrobial action[4].
While these findings are promising, more research is needed to entirely understand diosmin's potential in these areas.
Citations:
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